Basel, Switzerland
Internship Explorer
Internship Explorer
We are offering a unique opportunity to join the Structural Biology team in the Roche Innovation Center in Basel. The Internship is based within Lead Discovery, a part of Roche Pharma Research and Early Development, in collaboration with Antibody and Protein Technologies of Roche Diagnostics. The Structural Biology team delivers cutting-edge structural insights for all research and development across Roche, including small and large molecule research, genomic medicine and diagnostic solution. We are a diverse group of individuals with a broad range of deep expertise in X-ray crystallography, cryo electron microscopy (cryo-EM), protein purification and biophysical methods. We are looking for a talented master or bachelor student to support the structural biology team in delivering high quality protein structures and insights for our Diagnostics colleagues. The student will have access to world-class X-ray crystallography and cryo-EM facilities. This is a fantastic opportunity for someone who wants to further their practical knowledge in cryo-EM and X-ray crystallography methods while obtaining insights into how these methods are applied in the diagnostics and pharmaceutical industry. The Opportunity * Be integrated into the Structural Biology team within Lead Discovery. * Work closely in a highly collaborative spirit with Diagnostics colleagues in Germany and USA. * Perform and learn wet-lab experiments on proteins, such as high-throughput crystallisation screening, cryo-EM grid preparation and SPS-PAGE analysis, with the ultimate aim of generating 3D protein structures. * Use and learn IT tools to solve and build protein structures by X-ray crystallography and/or cryo-EM. * Plan experiments independently and present your results to stakeholders and within group seminars. * Learn how structural biology is a key tool in drug discovery and diagnostics research.
