Basel, Switzerland
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Development of metal-catalyzed reactions for general application and internal Roche projects. Synthesis and characterization of new ligands and metal catalysts under strict exclusion of air. Benchmarking newly prepared catalysts in standard reactions like cross-couplings and asymmetric hydrogenations. Integration of catalysts into ongoing Roche process steps and project workflows. Operation of metal-catalyzed reactions under pressure using autoclaves. Safe handling of gases such as H2 and CO in high-pressure environments. Utilization of state-of-the-art laboratory equipment including parallel screening reactors and glove boxes.
